They further suggest that Tap/NXT may play a role in remodeling of cytoplasmic RNP complexes, providing a link between export pathways and cytoplasmic fate. Taken together, our results indicate that Tap and NXT serve a role in translational regulation of RNA after export to the cytoplasm. Furthermore, Tap, but not NXT is detected in polyribosomes. Sucrose gradient analysis demonstrates that Tap and NXT efficiently shift the unspliced RNA into polyribosomal fractions. Pulse chase experiments show that Tap/NXT significantly increases the rate of protein synthesis. Here we show that Tap and NXT proteins function together to enhance translation of proteins from the exported CTE RNA. We have previously demonstrated that unspliced intron-containing CTE RNA is efficiently exported to the cytoplasm in mammalian cells. Tap forms a functional heterodimer with NXT/p15. If you have any questions, please call the Water Quality Laboratory at 61, if no answer, please leave a message or email us.Tap has been proposed to play a role in general mRNA export and also functions in expression of RNA with retained introns that contain the MPMV CTE (constitutive transport element). Best case is after the tap water in the plumbing has been flushed and is likely to contain extremely low levels or detect no lead at all.
Worst case is where the tap water is left standing in the plumbing for a period of time and is likely to see an extremely low level of lead if lead is present in the plumbing. The test is designed to demonstrate a worst case/best case scenario. We will get your results in approximately two weeks. All the resident needs to do is come by pick up the kit, read the instructions, fill out the form, fill the sample bottles according to the instructions, and return everything back to the lobby.
#Massachusetts tap forms how to#
There is a self-serve kiosk to the left of the lobby reception desk where residents can pick up and drop off the test kits.Ī test kit contains two bottles, a form to fill out, and specific instructions on how to collect the samples. We have tap water sampling kits available in the lobby of the water treatment facility at 250 Fresh Pond Parkway. We are happy to test residents' water for free, provided the resident collects the samples properly. To minimize the risk of exposure to copper and lead, always let your water run for a moment to flush out any standing water in your plumbing and bring in fresh water from our supply mains. We do many tests annually for Cambridge Residents and we find only very tiny amounts of copper and lead well below the EPA guidelines and is considered safe to drink. Water is a solvent and given enough time the tap water can leach out (absorb) copper and possibly lead. Prior to 1986, copper plumbing pipes could have been soldered together with a mixture of lead and zinc. Most tap water plumbing is made out of copper pipes soldered (joined) together with zinc solder. What buildings and residences do change chemically is the amount of lead and copper present in the internal plumbing. The tap water that is distributed is chemically very uniform throughout the city and in buildings and residences.
Cambridge water has its own unique fingerprint that is clearly identifiable from all other water.
#Massachusetts tap forms free#
The Cambridge Water Department offers free tap water testing for lead and copper to Cambridge residents.Įveryone consuming tap water in Cambridge gets their water from the same source.
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